Synaptigen cognitive wellness formula with probiotic and plant-based ingredients
The Formula

Synaptigen® Ingredients — Every Component, Explained

Synaptigen combines probiotic strains, a prebiotic fiber and two plant-based extracts in one daily formula. Here's what's inside, why each ingredient is included, and how to check the current Supplement Facts panel for your product.

Three targeted probiotic strains
Inulin as a prebiotic fiber
Strawberry and Peppermint plant extracts
Made in a GMP-certified, FDA-registered facility

★★★★★ Daily Cognitive Wellness  •  Six-ingredient formula  •  Satisfaction guarantee

Reviewed by the Synaptigen Editorial Team Product information reviewed for accuracy Last updated 14 September 2026 Sources: NIH, NCCIH, FDA
Synaptigen cognitive wellness supplement bottle
Formula overview

How the Synaptigen formula is put together

Synaptigen pairs probiotic strains with a prebiotic fiber and two plant-based extracts, built around a single idea: everyday support for the gut-brain connection.

Each ingredient plays a defined role. The probiotic strains are included for their association with microbiome balance, Inulin is included as a prebiotic to complement those strains, and the Strawberry and Peppermint extracts contribute plant-derived components to round out the formula.

None of these ingredients are intended to treat, cure or prevent any disease. They are included as part of a general cognitive-wellness formula meant to complement — not replace — adequate sleep, balanced nutrition, regular activity and other healthy habits.

Formulas can be updated as new research or sourcing considerations emerge. The Supplement Facts panel printed on your current bottle is always the most accurate and current source for exact ingredients, strains and amounts.

Full breakdown

Synaptigen™ Ingredients, One by One

A closer look at each ingredient in the Synaptigen formula, what category it belongs to, and why it's included as part of a daily cognitive-wellness routine.

Gut-brain support

Lactobacillus Paracasei

Lactobacillus Paracasei is a probiotic microorganism included in the Synaptigen™ formula as part of its gut-brain approach. Probiotic ingredients are commonly used in wellness formulas to support a balanced microbial environment, making this strain a key component of Synaptigen™ daily cognitive-wellness support.

Microbiome balance

Lactobacillus Reuteri

Lactobacillus Reuteri is another probiotic strain featured in Synaptigen™. It is included as part of the formula's focus on supporting a balanced microbial environment, which reflects the broader connection between digestive and cognitive wellness.

Daily microbiome support

Bifidobacterium Lactis BL-04

Bifidobacterium Lactis BL-04 is a defined probiotic strain used in Synaptigen™ to complement its cognitive-wellness formula. Bifidobacterium species are widely used in nutritional formulas because of their association with digestive and microbiome wellness, and BL-04 contributes to the product's probiotic blend.

Prebiotic fiber

Inulin

Inulin is included among the components of Synaptigen™ as a naturally occurring prebiotic fiber. Unlike probiotics, which provide live microorganisms, prebiotics provide a source of nourishment for certain beneficial gut bacteria, complementing the probiotic strains in the formula.

Plant-based component

Strawberry Extract

Strawberry Extract adds a plant-derived component to Synaptigen™. Strawberries naturally contain a variety of phytochemicals, and the extract is included as part of the product's broader nutritional approach rather than as a treatment for any medical condition.

Formula support

Peppermint Extract

Peppermint Extract is included as the second botanical component of Synaptigen™. Peppermint has a familiar refreshing profile and is widely used in nutritional products, complementing the other ingredients without being presented as a standalone therapeutic ingredient.

Important: Synaptigen™ is a dietary supplement intended to complement, not replace, a healthy lifestyle. Ingredient names, amounts, strains and serving recommendations may change with product updates. Always review the current Synaptigen™ Supplement Facts panel and product label before use, and speak with a qualified healthcare professional if you have questions about a specific ingredient.
Quick reference

Synaptigen ingredient categories at a glance

Ingredient Category Included for
Lactobacillus Paracasei Probiotic Gut-brain microbiome support
Lactobacillus Reuteri Probiotic Microbial balance
Bifidobacterium Lactis BL-04 Probiotic Daily microbiome support
Inulin Prebiotic Supports the probiotic strains
Strawberry Extract Plant-based Nutritional formula component
Peppermint Extract Plant-based Formula support

This table summarizes ingredient categories for general reference only. It is not a substitute for the Supplement Facts panel on your product, which lists exact amounts per serving.

Good to know

Reading the Synaptigen Supplement Facts panel

Every dietary supplement sold in the United States is required to include a Supplement Facts panel listing each active ingredient and its amount per serving. Before you start using Synaptigen, take a moment to review this panel on your bottle.

If you have known allergies or sensitivities, check the full ingredient list — including any inactive ingredients such as capsule material or flow agents — rather than relying only on the featured ingredients described on this page.

If you're taking prescription medication, managing a health condition, or are pregnant or nursing, talk to a doctor or pharmacist before adding Synaptigen or any new supplement to your routine. They can review your specific circumstances and flag any ingredient interactions to be aware of.

Synaptigen is manufactured in the United States in a facility that is FDA-registered and follows Good Manufacturing Practice (GMP) guidelines, which cover quality-control standards during production. This does not mean the FDA has evaluated or approved the finished product itself.

Common questions

Ingredient FAQ

Synaptigen is positioned around the gut-brain connection and includes several probiotic-oriented strains as part of the formula. Check the current Supplement Facts label for the specific strains, quantities and other active ingredients included in your product.

Yes, formulas can be updated over time. The Supplement Facts panel printed on your current product packaging is always the authoritative source for exact ingredients, strains and amounts — not this page or any other marketing material.

No. Synaptigen ingredients are included for general cognitive-wellness support and are not intended to diagnose, treat, cure or prevent dementia, Alzheimer's disease or any other medical condition. If you have ongoing memory or cognitive symptoms, see a qualified healthcare professional.

If you take prescription or over-the-counter medication, use other supplements, have allergies or manage a health condition, speak with your doctor or pharmacist before starting Synaptigen so they can review your individual circumstances.
Synaptigen six-bottle cognitive wellness package
Regular price: $99 per Bottle
Today from $49 per Bottle
View the Synaptigen Offer

Includes the stated 180-day money-back guarantee. Review the current offer and purchase terms on the official order page.

Order Synaptigen — From $49 180-day money-back guarantee • Official website only